This procedure is performed in selected patients who have aspirin-exacerbated respiratory disease or AERD (previously known as Samter’s triad) – a condition that is characterized by aspirin or NSAID-induced respiratory reactions in patients with underlying chronic respiratory diseases such as asthma, rhinitis, sinusitis, and/or nasal polyps.
This is a specialized procedure that is performed over a few days with the goal of inducing one’s ability to temporarily tolerate aspirin. Increasing doses of aspirin are given starting with a very small dose and patients are observed and assessed between doses and throughout the procedure. After completing the procedure, the patient will take aspirin daily in order to maintain this ability to tolerate aspirin. Prior to undergoing this procedure, your allergist will assess your lung function and determine what medications you should be taking.
Note: NSAID refers to “non-steroidal anti-inflammatory drugs” and they are in the same family as aspirin. These include ibuprofen, Motrin Advil, naproxen, Aleve.